Mbd2 - methyl-CpG binding domain protein 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 680172

Summary

Enables chromatin binding activity. Involved in several processes, including maternal behavior; positive regulation of chromatin binding activity; and regulation of nucleobase-containing compound metabolic process. Located in chromatin. Used to study choline deficiency disease. Biomarker of choline deficiency disease; transient cerebral ischemia; and visual epilepsy. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human MBD2 (methyl-CpG binding domain protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Mbd2 Products (1)

mRNA Protein Name
NM_001115025.1 NP_001108497.1 methyl-CpG-binding domain protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
25135974 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to organic cyclic compound IEP
IEP: Inferred from expression pattern
25135974 RGD
involved in embryonic organ development IEP
IEP: Inferred from expression pattern
12672019 RGD
involved in epigenetic regulation of gene expression IEP
IEP: Inferred from expression pattern
20735989 RGD
involved in maternal behavior IEP
IEP: Inferred from expression pattern
25135974 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
25135974 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
22109888 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
25135974 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
16702315 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
22109888 RGD
involved in ventricular cardiac muscle tissue development IEP
IEP: Inferred from expression pattern
20735989 RGD
Cellular Component GO Annotation Evidence References Source
located in chromatin IDA
IDA: Inferred from direct assay
25135974 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methyl-CpG-binding domain protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-131031 KCC-07 99.97% Unkown
HY-RS08182 MBD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-128562 CS-1-69 / Unkown
HY-179238 CS-1-103 Inhibitor / Unkown
HY-186232 CS-1-102 / Unkown
HY-186233 CS-1-174 Inhibitor / Unkown
HY-RS03948 DPEP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17814 Mbd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18658 Dpep2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24283 Mbd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mbd2 NCBI NCBI:8932