Psmd1 - proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 Gene

Also Known as S1; P112; 2410026J11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70247

Summary

In eukaryotic cells, most proteins in the cytosol and nucleus are degraded via the ubiquitin-proteasome pathway. The 26S Proteasome is a self-compartmentalizing protease comprised of approximately 31 different subunits. It contains a barrel-shaped proteolytic core complex (the 20S Proteasome), capped at one or both ends by 19S regulatory complexes, which recognize ubiquitinated proteins. Protein degradation by proteasomes is the source of most antigenic peptides presented on MHC class I molecules. This gene encodes a non-ATPase subunit of the 26S Proteasome. [provided by RefSeq, Jul 2008]

Psmd1 Products (1)

mRNA Protein Name
NM_027357.2 NP_081633.1 26S proteasome non-ATPase regulatory subunit 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16973439 MGI
Cellular Component GO Annotation Evidence References Source
part of proteasome accessory complex IDA
IDA: Inferred from direct assay
16857966 MGI
part of proteasome complex IDA
IDA: Inferred from direct assay
16973439 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

26S proteasome non-ATPase regulatory subunit 1

  • 26S proteasome regulatory subunit RPN2

  • 26S proteasome regulatory subunit S1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11317 PSMD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22748 Psmd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29262 Psmd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Psmd1 NCBI NCBI:5707