VIPR2 - vasoactive intestinal peptide receptor 2 Gene
Also Known as VPAC2; VPAC2R; VIP-R-2; VPCAP2R; PACAP-R3; DUP7q36.3; PACAP-R-3; C16DUPq36.3
Species: Homo sapiens
About VIPR2
This gene has 4 transcripts (splice variants), 259 orthologues and 42 paralogues. Broad expression in ovary (RPKM 1.9), brain (RPKM 1.9) and 20 other tissues.
Summary
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates Adenylate Cyclase. [provided by RefSeq, Aug 2011]
VIPR2 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001304522.2 | NP_001291451.1 | vasoactive intestinal polypeptide receptor 2 isoform 2 precursor |
| NM_001308259.1 | NP_001295188.1 | vasoactive intestinal polypeptide receptor 2 isoform 3 |
| NM_003382.5 | NP_003373.2 | vasoactive intestinal polypeptide receptor 2 isoform 1 precursor |
VIPR2 Protein Structure
HRM: Hormone receptor domain (50 - 111)
7tm_2: 7 transmembrane receptor (Secretin family) (125 - 371)
- 0
- 100
- 200
- 300
- 400
- 438 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
vasoactive intestinal polypeptide receptor 2 |
|
Recombinant VIPR2 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P76128 | VIPR2 Protein, Human (HEK293, Fc) | P41587 (E24-V126) | ≥ 95%, as determined by reducing SDS-PAGE. |
VIPR2 Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P81526 | VPAC2 Antibody (YA1271) | IHC-P | Human |
| HY-P81526A | VPAC2 Antibody (YA1271)(PBS only) | IHC-P | Human |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Schizophrenia 16 |
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| Gastric Leiomyoma |
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| Central Serous Chorioretinopathy |
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| Holoprosencephaly |
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| Myopia |
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| Sudden Infant Death Syndrome |
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| Advanced Sleep Phase Syndrome |
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| Isolated Growth Hormone Deficiency, Type Ib |
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| Major Depressive Disorder |
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| Intellectual Developmental Disorder, X-Linked, Syndromic, Wilson-Turner Type |
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| Schizophrenia |
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| Migraine With Or Without Aura 1 |
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| Attention Deficit-Hyperactivity Disorder |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | VIPR2 | VGNC | VGNC:48266 |
| Bos taurus | VIPR2 | VGNC | VGNC:36800 |
| Mus musculus | VIPR2 | MGD | MGI:107166 |
| Rattus norvegicus | VIPR2 | RGD | RGD:3962 |
| Felis catus | VIPR2 | VGNC | VGNC:66946 |
| Macaca mulatta | VIPR2 | VGNC | VGNC:78772 |
| Others | VIPR2 | NCBI |