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79961

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Inhibitors & Agonists

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Peptides

7

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-180571

    PROTACs CCR Cancer
    LUF7996 is a CCR2 PROTAC Degrader degrading CCR2 with DC50 = 2.6 μM. LUF7996 demonstrates engagement of both and the E3 ligase cereblon and displays sustain and concentration-dependent degradation of CCR2. LUF7996 reliance on the lysosomal pathway to induce CCR2 degradation. LUF7996 efficiently inhibits monocyte migration in virto .
    LUF7996

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