RND2 - Rho family GTPase 2 Gene

Homo sapiens

Also known as ARHN; RHO7; RhoN

Gene ID: 8153 | Gene type: protein coding

About RND2

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:43,025,231-43,032,041 (from NCBI)

This gene has 2 transcripts (splice variants), 263 orthologues and 22 paralogues. Biased expression in brain (RPKM 14.7), testis (RPKM 13.8) and 5 other tissues.

Summary

This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin Cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian Cancer susceptibility gene BRCA1. [provided by RefSeq, Jul 2008]

RND2 Products(1)

mRNA	Protein	Name
NM_005440.5	NP_005431.1	rho-related GTP-binding protein RhoN

RND2 Protein Structure

Ras

0
100
200
227 a.a.

Protein Preferred Names

Protein Names

rho-related GTP-binding protein RhoN

CTD-3199J23.4

Related Diseases

Diseases

Alias

Ascaridiasis

Ascariasis

Toxic Megacolon

Megacolon, Toxic	Toxic Dilatation Of Colon
Toxic Functional Megacolon

Clostridium Difficile Colitis

Pseudomembranous Colitis	Colitis Pseudomembranous
Enterocolitis, Pseudomembranous	Pseudomembranous Enterocolitis
Clostridium Difficile Infection

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12032	RND2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	RND2	VGNC	VGNC:64662
Bos taurus	RND2	VGNC	VGNC:34005
Mus musculus	RND2	MGD	MGI:1338755
Macaca mulatta	RND2	VGNC	VGNC:76765
Rattus norvegicus	RND2	RGD	RGD:1306172
Canis familiaris	RND2	VGNC	VGNC:45617