FGF16 - fibroblast growth factor 16 Gene

Homo sapiens

Also known as MF4; FGF-16

Gene ID: 8823 | Gene type: protein coding

About FGF16

Cytogenetic location: Xq21.1 Genomic coordinates (GRCh38): X:77,447,389-77,457,278 (from NCBI)

This gene has 1 transcript (splice variant), 196 orthologues, 21 paralogues and is associated with 2 phenotypes. Low expression observed in reference dataset.

Summary

This gene encodes a member of a family of proteins that are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene is expressed in cardiac cells and is required for proper heart development. Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion. [provided by RefSeq, Mar 2014]

FGF16 Products(1)

mRNA	Protein	Name
NM_003868.3	NP_003859.1	fibroblast growth factor 16

FGF16 Protein Structure

FGF

0
100
116 a.a.

Protein Preferred Names

Protein Names

fibroblast growth factor 16

metacarpal 4-5 fusion

Recombinant FGF16 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7344	FGF-16 Protein, Human (CHO)	O43320 (A2-R207)	≥95%
HY-P700059AF	Animal-Free FGF-16 Protein, Human (His)	O43320 (A1-R207)	≥95%

Related Diseases

Diseases

Alias

Metacarpal 4-5 Fusion

Syndactyly Type 8	MF4
Fusion Of Metacarpals 4 And 5	Metacarpals 4 And 5 Fusion
Metacarpal 4 5 Fusion

Syndactyly, Type Iii

Syndactyly Type 3	SDTY3
Ring And Little Finger Syndactyly	Syndactyly Of Fingers Iv And V
Syndactyly Of Fingers 4 And 5	Ringand Little Finger Syndactyly
Syndactyly Of Fingers Four And Five	Syndactyly Of The Ring And Little Finger
Sd3	Syndactyly 3
Syndactyly Type Iii	4-5 Finger Syndactyly
Syndactyly, Type 3

Zygodactyly 1

Zd1	Zygodactyly Type 1
Sd1, Weidenreich Type	Sd1a
Syndactyly Type 1, Weidenreich Type	Syndactyly Type 1a
Zygodactyly, Weidenreich Type

Chromosome 2q35 Duplication Syndrome

Syndactyly	Syndactyly Type 1
Sdty1	Zygodactyly
Syndactyly, Type I	Sd1
Syndactyly, Type 1, With Or Without Craniosynostosis	Symphalangism
Non-Syndromic Syndactyly	Symphalangy
Webbing Of Digits	Syndactyly, Type 1

Syndactyly, Type Iv

Syndactyly Type 4	Polysyndactyly, Haas Type
SDTY4	Haas Type Syndactyly
Sd4	Polysyndactyly Type Haas
Syndactyly 4	Polysyndactyly Haas Type
Syndactyly Type Iv

Beare-Stevenson Cutis Gyrata Syndrome

Cutis Gyrata Syndrome Of Beare And Stevenson	Beare-Stevenson Syndrome
BSTVS	Cutis Gyrata-Acanthosis Nigricans-Craniosynostosis Syndrome
Beare Stevenson Syndrome	Cutis Gyrata - Acanthosis Nigricans - Craniosynostosis
Cutis Gyrata Syndrome Of Beare-Stevenson

Achondroplasia, Severe, With Developmental Delay And Acanthosis Nigricans

SADDAN	Saddan Dysplasia
Severe Achondroplasia With Developmental Delay And Acanthosis Nigricans	Severe Achondroplasia-Developmental Delay-Acanthosis Nigricans Syndrome
Ssb Syndrome	Skeleton Skin Brain Syndrome
Skeleton-Skin-Brain Syndrome	Achondroplasia

Poland Syndrome

Poland Anomaly	Poland Sequence
Poland Syndactyly	Poland'S Syndrome
Poland'S Anomaly	Poland'S Syndactyly
Acro-Pectoro-Renal Field Defect	Brachydactyly, Absent Pectoral Muscles And Agenesis/Hypoplasia Of Kidneys
Unilateral Defect Of Pectoralis Muscle And Syndactyly Of The Hand	Unilateral Defect Of Pectoralis Major And Syndactyly Of The Hand

Multiple Synostoses Syndrome

Symphalangism-Brachydactyly Syndrome	Deafness-Hermann Type Symphalangism Syndrome
Facio-Audio-Symphalangism	Hearing Loss-Hermann Type Symphalangism Syndrome
Wl Syndrome	Multiple Synostosis Syndrome

Crouzon Syndrome

Crouzon Craniofacial Dysostosis	Craniofacial Dysostosis
Cfd1	Craniofacial Dysostosis Type 1
Crouzon Disease	Crouzon'S Disease
Craniofacial Dysostosis, Type I	Craniofacial Dysarthrosis
Craniofacial Dysostosis Syndrome	CS
Craniofacial Dysostosis Type I	Vogt Cephalosyndactyly

Cardiomyopathy, Familial Hypertrophic, 1

Asymmetric Septal Hypertrophy	Familial Hypertrophic Cardiomyopathy
Hypertrophic Cardiomyopathy 1	CMH1
Hypertrophic Cardiomyopathy 19	CMH
Ventricular Hypertrophy, Hereditary	Ash
Hypertrophic Subaortic Stenosis, Idiopathic	Cardiomyopathy, Familial Hypertrophic
Cardiomyopathy, Hypertrophic, 1, Digenic	Cardiomyopathy, Familial Hypertrophic 1
Hcm	Hereditary Ventricular Hypertrophy
Idiopathic Hypertrophic Subaortic Stenosis	Hypertrophic Cardiomyopathy
Cardiomyopathy, Hypertrophic, Familial	Cardiomyopathy, Hypertrophic, 1
Familial Asymmetric Septal Hypertrophy	Heritable Hypertrophic Cardiomyopathy
Fhc	Cardiomyopathy, Hypertrophic, Familial, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04892	FGF16 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	FGF16	VGNC	VGNC:62248
Macaca mulatta	FGF16	VGNC	VGNC:72646
Rattus norvegicus	FGF16	RGD	RGD:71052
Bos taurus	FGF16	VGNC	VGNC:28973
Mus musculus	FGF16	MGD	MGI:1931627
Canis familiaris	FGF16	VGNC	VGNC:40843

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