RAB11B - RAB11B, member RAS oncogene family Gene

Homo sapiens

Also known as H-YPT3; NDAGSCW

Gene ID: 9230 | Gene type: protein coding

About RAB11B

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:8,390,360-8,404,434 (from NCBI)

This gene has 5 transcripts (splice variants), 115 orthologues, 68 paralogues and is associated with 2 phenotypes. Ubiquitous expression in fat (RPKM 36.5), thyroid (RPKM 36.2) and 25 other tissues.

Summary

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]

RAB11B Products(1)

mRNA	Protein	Name
NM_004218.4	NP_004209.2	ras-related protein Rab-11B

RAB11B Protein Structure

Ras

0
100
200
218 a.a.

Protein Preferred Names

Protein Names

ras-related protein Rab-11B

GTP-binding protein YPT3

Recombinant RAB11B Proteins

Cat. No.	Product Name	Accession	Purity
HY-P74610	RAB11B Protein, Human (HEK293, His)	Q15907-1 (G2-C215)	≥95%

Related Diseases

Diseases

Alias

Neurodevelopmental Disorder With Ataxic Gait, Absent Speech, And Decreased Cortical White Matter

NDAGSCW

Neurodevelopmental Disorder With Ataxic Gait, Absent Speech, Decreased Cortical White Matter

Esophagus Sarcoma

Esophageal Sarcoma

Hypotrichosis 3

HYPT3	Hypotrichosis Simplex Of The Scalp 2
Htss2	Hypotrichosis, Type 3

Rectum Adenocarcinoma

Rectal Adenocarcinoma

Adenocarcinoma Of Rectum

Rectal Benign Neoplasm

Neoplasm Of Rectum	Rectal Tumor
Rectum Neoplasm	Neoplasm Of The Rectum
Rectal Neoplasms	Primary Rectal Cancer
Rectal Ampulla Cancer	Cancer Of The Rectum
Carcinoma Of Rectum	Primary Malignant Neoplasm Of Rectum
Rectal Cancer	Rectal Carcinoma

Rectum Cancer

Malignant Neoplasm Of Rectum	Rectal Cancer
Cancer Of Rectum	Carcinoma Of Rectum
Carcinoma Of The Rectum	Malignant Rectal Tumor
Malignant Rectum Tumor	Malignant Tumor Of Rectum
Rectal Carcinoma	Rectal Cancers
Cancer, Rectal

Cystic Fibrosis

Mucoviscidosis	CF
Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis	Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis
Cystic Fibrosis Lung Disease, Modifier Of	Cystic Fibrosis Of Pancreas
Fibrocystic Disease Of Pancreas	Cf - [Cystic Fibrosis]
Cystic Fibrosis Nos	Fibrocystic Disease
Fibrocystic Disease Of The Pancreas	Mucoviscidosis Of Pancreas
Nonproliferative Fibrocystic Disease	Pancreatic Cystic Fibrosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11516	RAB11B Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	RAB11B	VGNC	VGNC:81518
Mus musculus	RAB11B	MGD	MGI:99425
Felis catus	RAB11B	VGNC	VGNC:97580
Canis familiaris	RAB11B	VGNC	VGNC:45249
Rattus norvegicus	RAB11B	RGD	RGD:68369
Bos taurus	RAB11B	VGNC	VGNC:33615
Others	RAB11B	NCBI

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