SH3BP5L - SH3 binding domain protein 5 like Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 80851

Summary

Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in skin (RPKM 5.3), brain (RPKM 5.2) and 25 other tissues.

SH3BP5L Products (4)

mRNA Protein Name
NM_001322462.1 NP_001309391.1 SH3 domain-binding protein 5-like isoform 2
NM_001322463.1 NP_001309392.1 SH3 domain-binding protein 5-like isoform 2
NM_001322464.2 NP_001309393.1 SH3 domain-binding protein 5-like isoform 3
NM_030645.3 NP_085148.1 SH3 domain-binding protein 5-like isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
30217979 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
15161933 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SH3BP5L Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
SH3BP5L Q7L8J4 CEP57 Homo sapiens Q86XR8-3
Validated Y2H
32296183
Intra
SH3BP5L Q7L8J4 YWHAZ Homo sapiens P63104
Pull Down
15161933
Intra
SH3BP5L Q7L8J4 YWHAZ Homo sapiens P63104
Anti Tag CoIP
33961781
Intra
SH3BP5L Q7L8J4 RAB11B Homo sapiens Q15907
Anti Tag CoIP
33961781
Intra
SH3BP5L Q7L8J4 FAM161B Homo sapiens Q96MY7
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS12833 SH3BP5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21931 Sh3bp5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28447 Sh3bp5 Rat Pre-designed siRNA Set A / Unkown