2. Gene
  3. MOB1B - MOB kinase activator 1B Gene

MOB1B - MOB kinase activator 1B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MATS2; MOB4A; MOBKL1A

Gene ID: 92597 | Gene type: protein coding

About MOB1B

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:70,901,851-70,988,168 (from NCBI)

This gene has 5 transcripts (splice variants), 216 orthologues and 6 paralogues. Ubiquitous expression in kidney (RPKM 9.7), bone marrow (RPKM 8.6) and 25 other tissues.

Summary

The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

MOB1B Products(3)

mRNA Protein Name
NM_001244766.2 NP_001231695.1 MOB kinase activator 1B isoform 1
NM_001244767.2 NP_001231696.1 MOB kinase activator 1B isoform 3
NM_173468.4 NP_775739.1 MOB kinase activator 1B isoform 2

MOB1B Protein Structure

Mob1_phocein

Mob1_phocein: Mob1/phocein family (30 - 205)

  • 0
  • 100
  • 200
  • 216 a.a.
Protein Preferred Names Protein Names

MOB kinase activator 1B

MOB1 Mps One Binder homolog B

Recombinant MOB1B Proteins

Cat. No. Product Name Accession Purity
HY-P77449 MOB4A/MOB1B Protein, Human (His) Q7L9L4 (M1-R216) ≥95%

Related Diseases

Diseases Alias
Sveinsson Chorioretinal Atrophy

SCRA

Atrophia Areata

Helicoid Peripapillary Chorioretinal Degeneration

Hpcd

Aa

Peripapillary Chorioretinal Degeneration, Icelandic Type

Helicoidal Peripapillary Chorioretinal Degeneration

Atrophy, Chorioretinal, Sveinsson
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08574 MOB1B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris MOB1B VGNC VGNC:43300
Macaca mulatta MOB1B VGNC VGNC:74863
Rattus norvegicus MOB1B RGD RGD:1305114
Mus musculus MOB1B MGD MGI:1915723
Felis catus MOB1B VGNC VGNC:63544
Bos taurus MOB1B VGNC VGNC:31542
Others MOB1B NCBI