Prdx6 - peroxiredoxin 6 Gene

Also Known as LPCAT-5

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 94167

Summary

Enables 1-acylglycerophosphocholine O-acyltransferase activity and Glutathione Peroxidase activity. Involved in hydrogen peroxide catabolic process. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be active in cytosol and mitochondrion. Orthologous to human PRDX6 (peroxiredoxin 6). [provided by Alliance of Genome Resources, Apr 2022]

Prdx6 Products (1)

mRNA Protein Name
NM_053576.2 NP_446028.1 peroxiredoxin-6

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables 1-acylglycerophosphocholine O-acyltransferase activity IDA
IDA: Inferred from direct assay
26830860 RGD
enables glutathione peroxidase activity IDA
IDA: Inferred from direct assay
8641418 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
17877381 RGD
Biological Process GO Annotation Evidence References Source
involved in hydrogen peroxide catabolic process IDA
IDA: Inferred from direct assay
8641418 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxiredoxin-6

  • 1-Cys PRX

  • 1-Cys peroxiredoxin

  • LPC acyltransferase 5

  • NSGPx

  • acidic calcium-independent phospholipase A2

  • aiPLA2

  • antioxidant protein 2

  • glutathione-dependent peroxiredoxin

  • lyso-PC acyltransferase 5

  • lysophosphatidylcholine acyltransferase 5

  • non-seleni

Prdx6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Prdx6 O35244 Ywhae Mus musculus P62259
Pull Down
21346153
Cross
Prdx6 O35244 Ywhae Mus musculus P62259
SPR
21346153
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-115062 MJ33 lithium salt Inhibitor 99.0% Unkown
HY-129944A MJ33-OH lithium Inhibitor ≥90.0% Unkown
HY-RS11078 PRDX5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-129944 MJ33-OH Inhibitor / Unkown
HY-136271 MJ33 Inhibitor / Unkown
HY-RS11079 PRDX6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17470 Prdx6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17919 Prdx5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23928 Prdx6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prdx6 NCBI NCBI:9588