1. Gene
  2. OXSR1 - oxidative stress responsive kinase 1 Gene

OXSR1 - oxidative stress responsive kinase 1 Gene

Homo sapiens

Also known as OSR1

Gene ID: 9943 | Gene type: protein coding

About OXSR1

Cytogenetic location: 3p22.2 Genomic coordinates (GRCh38): 3:38,164,063-38,255,484 (from NCBI)

This gene has 6 transcripts (splice variants), 98 orthologues and 35 paralogues. Ubiquitous expression in esophagus (RPKM 13.6), bone marrow (RPKM 11.2) and 25 other tissues.

Summary

The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin Cytoskeleton. [provided by RefSeq, Jul 2008]

OXSR1 Products(1)

mRNA Protein Name
NM_005109.3 NP_005100.1 serine/threonine-protein kinase OSR1

OXSR1 Protein Structure

Pkinase

Pkinase: Protein kinase domain (17 - 291)

OSR1_C

OSR1_C: Oxidative-stress-responsive kinase 1 C-terminal domain (434 - 464)

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  • 527 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase OSR1

oxidative stress responsive 1

Recombinant OXSR1 Proteins

Cat. No. Product Name Accession Purity
HY-P77119 OXSR1 Protein, Human (sf9, GST) O95747 (M1-S527) ≥95%

Related Diseases

Diseases Alias
Hypomagnesemia 4, Renal

Renal Hypomagnesemia 4

HOMG4

Hypomagnesemia, Renal, Normocalciuric

Hypomagnesemia 4

Renal Hypomagnesemia Normocalciuric

Hypomagnesemia, Type 4, Renal

Arthrogryposis, Distal, Type 3

Gordon Syndrome

DA3

Distal Arthrogryposis Type 3

Arthrogryposis Multiplex Congenita, Distal, Type Iia

Camptodactyly, Cleft Palate, And Clubfoot

Camptodactyly-Cleft Palate-Clubfoot Syndrome

Distal Arthrogryposis Multiplex Congenita Type Iia

Arthrogryposis Distal Type 3

Distal Arthrogryposis Type Iia

Arthrogryposis, Distal, 3

Pseudohypoaldosteronism, Type Ii

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus OXSR1 RGD RGD:1310466
Felis catus OXSR1 VGNC VGNC:97546
Macaca mulatta OXSR1 VGNC VGNC:81491
Mus musculus OXSR1 MGD MGI:1917378
Canis familiaris OXSR1 VGNC VGNC:44205
Bos taurus OXSR1 VGNC VGNC:32514
Others OXSR1 NCBI