GLP-1R agonist 3
Based on 1 Customer Validation
GLP-1R agonist 3 is a potent agonist of GLP-1R. GLP-1R agonist 3 is a thickened imidazole derivative compound. Glucagon-like peptide-1 (GLP-1) is an intestinal hypoglycemic hormone secreted by L-cells in the lower gastrointestinal tract. GLP-1R agonist 3 has the potential for the research of diabetes (extracted from patent WO2021197464A1, compound 1).
For research use only. We do not sell to patients.
- Purity: 95.76%
- CAS No.: 2428640-18-8
- Formula: C31H28FN5O4
- Molecular Weight:553.58
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 2428640-18-8
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Appearance Solid
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Molecular Weight 553.58
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Formula C31H28FN5O4
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Color White to light yellow
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SMILES
FC(C=C(C=C1)C#N)=C1COC2=NC(C3=CCN(CC3)CC(N(C4=C5)C[C@@H]6CCO6)=NC4=CC=C5C(O)=O)=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (225.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8064 mL | 9.0321 mL | 18.0642 mL | 45.1606 mL |
| 5 mM | 0.3613 mL | 1.8064 mL | 3.6128 mL | 9.0321 mL | |
| 10 mM | 0.1806 mL | 0.9032 mL | 1.8064 mL | 4.5161 mL | |
| 15 mM | 0.1204 mL | 0.6021 mL | 1.2043 mL | 3.0107 mL | |
| 20 mM | 0.0903 mL | 0.4516 mL | 0.9032 mL | 2.2580 mL | |
| 25 mM | 0.0723 mL | 0.3613 mL | 0.7226 mL | 1.8064 mL | |
| 30 mM | 0.0602 mL | 0.3011 mL | 0.6021 mL | 1.5054 mL | |
| 40 mM | 0.0452 mL | 0.2258 mL | 0.4516 mL | 1.1290 mL | |
| 50 mM | 0.0361 mL | 0.1806 mL | 0.3613 mL | 0.9032 mL | |
| 60 mM | 0.0301 mL | 0.1505 mL | 0.3011 mL | 0.7527 mL | |
| 80 mM | 0.0226 mL | 0.1129 mL | 0.2258 mL | 0.5645 mL | |
| 100 mM | 0.0181 mL | 0.0903 mL | 0.1806 mL | 0.4516 mL |