GluN2A Allosteric modulator 1
GluN2A Allosteric modulator 1 (Compound 11) is an orally active, BBB-penetrable and highly selective GluN2A negative allosteric modulator. GluN2A Allosteric modulator 1 has IC50 values of 0.042 μM and 13 μM for GluN2A and GluN2B, respectively. GluN2A Allosteric modulator 1 can be used for the research of nervous system diseases.
For research use only. We do not sell to patients.
- Formula: C20H16ClF2N5O2
- Molecular Weight:431.82
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All iGluR Isoforms
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Biological Activity
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GluN2A 0.042 μM (IC50) |
GluN2B 13 μM (IC50) |
Chemical Information
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Molecular Weight 431.82
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Formula C20H16ClF2N5O2
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SMILES
O=C(C1=NC=C(OCC(F)(C2=CC(Cl)=CC=C2)F)N=C1)NC3(C4=NC=CN=C4)CC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)