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  3. Grazoprevir impurity 1

Grazoprevir impurity 1 is an impurity of Grazoprevir (HY-15298).

For research use only. We do not sell to patients.

Grazoprevir impurity 1

Grazoprevir impurity 1 Chemical Structure

CAS No. : 1206524-79-9

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10 mM * 1 mL in DMSO
ready for reconstitution
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10 mM * 1 mL in DMSO In-stock
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Description

Grazoprevir impurity 1 is an impurity of Grazoprevir (HY-15298).

Molecular Weight

437.87

Formula

C20H24ClN3O6

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

COC1=CC=C(N=C(Cl)C(O[C@@H](CN2C(OC(C)(C)C)=O)C[C@H]2C(OC)=O)=N3)C3=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (228.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2838 mL 11.4189 mL 22.8378 mL
5 mM 0.4568 mL 2.2838 mL 4.5676 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 95.0%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2838 mL 11.4189 mL 22.8378 mL 57.0946 mL
5 mM 0.4568 mL 2.2838 mL 4.5676 mL 11.4189 mL
10 mM 0.2284 mL 1.1419 mL 2.2838 mL 5.7095 mL
15 mM 0.1523 mL 0.7613 mL 1.5225 mL 3.8063 mL
20 mM 0.1142 mL 0.5709 mL 1.1419 mL 2.8547 mL
25 mM 0.0914 mL 0.4568 mL 0.9135 mL 2.2838 mL
30 mM 0.0761 mL 0.3806 mL 0.7613 mL 1.9032 mL
40 mM 0.0571 mL 0.2855 mL 0.5709 mL 1.4274 mL
50 mM 0.0457 mL 0.2284 mL 0.4568 mL 1.1419 mL
60 mM 0.0381 mL 0.1903 mL 0.3806 mL 0.9516 mL
80 mM 0.0285 mL 0.1427 mL 0.2855 mL 0.7137 mL
100 mM 0.0228 mL 0.1142 mL 0.2284 mL 0.5709 mL
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Grazoprevir impurity 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Grazoprevir impurity 1
Cat. No.:
HY-78628
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