GSK-163090 dihydrochloride
GSK-163090 dihydrochloride is a potent, selective and orally active 5-HT1A/1B/1D receptor antagonist with pKi values of 9.4, 8.5 and 9.7, respectively. GSK-163090 dihydrochloride inhibits the functional activity of serotonin reuptake transporter (SerT) with a pKi value of 6.1. GSK-163090 dihydrochloride has antidepressant and anxiolytic activities.
For research use only. We do not sell to patients.
- CAS No.: 844903-52-2
- Formula: C25H31Cl2N5O
- Molecular Weight:488.45
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
5-HT1A Receptor 9.4 (pKi) |
5-HT1B Receptor 8.5 (pKi) |
5-HT1D Receptor 9.7 (pKi) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
CAS No. 844903-52-2
-
Molecular Weight 488.45
-
Formula C25H31Cl2N5O
-
SMILES
O=C1NCCN1C2=CC=CC(CCN3CCN(C4=C5C=CC(C)=NC5=CC=C4)CC3)=C2.Cl.Cl
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GSK-163090 dihydrochloride Related Classifications
HY-14349 Related Classifications
Powered by Bioz