GSK3011724A
GSK3011724A is a β-ketoacyl-ACP synthase (KasA) inhibitor with an IC50 of 0.01 μM. GSK3011724A inhibits the growth of Mycobacterium tuberculosis H37Rv. GSK3011724A can be used for research on tuberculosis.
For research use only. We do not sell to patients.
- CAS No.: 2293983-60-3
- Formula: C12H17N3O2S
- Molecular Weight:267.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>100 μM
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Cytotoxicity against human HepG2 cells with IC50 >100 μM.
Cytotoxicity against human HepG2 cells with IC50 >100 μM.
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32196311 |
In Vitro
GSK3011724A (1.7 μM; 6 days) has an MIC of 1.7 μM against M. tuberculosis H37Rv[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 2293983-60-3
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Molecular Weight 267.35
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Formula C12H17N3O2S
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SMILES
CCCCS(=O)(NC1=CC2=C(C=C1)C=NN2C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GSK3011724A Related Classifications
HY-125173 Related Classifications
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