GWP-042
Based on 2 publication(s) in Google Scholar
GWP-042 is a potent inhibitor of mycobacterial alanine dehydrogenase (Ald) Rv2780, with the IC50 of 0.21 μM. GWP-042 has antimicrobial activity against M. tuberculosis infection in vivo.
For research use only. We do not sell to patients.
- Purity: 95.63%
- CAS No.: 1645486-93-6
- Formula: C14H15FN4O2
- Molecular Weight:290.29
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) GWP-042
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Biological Activity
Chemical Information
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CAS No. 1645486-93-6
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Appearance Solid
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Molecular Weight 290.29
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Formula C14H15FN4O2
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Color White to off-white
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SMILES
O=C([C@@H]1CCCO1)NC2=NN=C(N2)CC3=CC(F)=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Nat Commun
Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine. [Abstract]2024 May 17;15(1):4216. PMID: 38760394 -
Solvent & Solubility
H2O : < 0.1 mg/mL (insoluble)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)