1. Others
  2. Others
  3. Halofenozide

Halofenozide (Synonyms: RH-0345)

Cat. No.: HY-113890
Handling Instructions

Halofenozide (RH-0345) is an ecdysteroid agonist. RH-0345 belongs to a new group of insect growth regulators (IGRs) with a benzoylhydrazine structure that mimic the action of the natural insect molting hormone 20-hydroxyecdysone.

For research use only. We do not sell to patients.

Halofenozide Chemical Structure

Halofenozide Chemical Structure

CAS No. : 112226-61-6

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Halofenozide (RH-0345) is an ecdysteroid agonist. RH-0345 belongs to a new group of insect growth regulators (IGRs) with a benzoylhydrazine structure that mimic the action of the natural insect molting hormone 20-hydroxyecdysone[1].

In Vitro

Halofenozide (RH-0345) reduces both growth and development of oocytes in vitro[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[2]

Cell Line: Cultured ovaries were dissected from female adult beetles of mealworm, Tenebrio molitor (T. molitor)
Concentration: 1 μM and 10 μM
Incubation Time: 4 days
Result: Did not cause a significant effect on ecdysteroid amounts in the culture medium using ovaries from 0- and 2-day-old females at 10 μM.
Caused a small significant increase of the amounts of ovarian ecdysteroids in the culture medium at 1 μM in the culture medium and with 2-day-old ovaries.
In Vivo

After topical application of Halofenozide (RH-0345; 5 and 10 μg) on adult females, the highest dose (10 μg) reduces significantly the reproductive parameters scored: namely the oviposition period, the fecundity and the egg viability[1].
Halofenozide at the two doses tested (5 and 10 μg) causes smaller eggs with a decrease in length, width and volume[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Newly emerged (0-day-old) adult females of T. molitor [1]
Dosage: 5 and 10 μg
Administration: Topically applied
Result: Caused smaller eggs with a decrease in length, width and volume at the two doses tested (5 and 10 μg) .
Molecular Weight

330.81

Formula

C₁₈H₁₉ClN₂O₂

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Halofenozide
Cat. No.:
HY-113890
Quantity:
MCE Japan Authorized Agent: