HIV-1 integrase inhibitor 12

HIV-1 integrase inhibitor 12 (Compound 17) is an inhibitor for HIV-1 integrase with an IC50 of 1.4 nM. HIV-1 integrase inhibitor 12 inhibits the HIV-1 WT and HIV-1 T125A, with IC50 of 7.4 and 120 nM, respectively. HIV-1 integrase inhibitor 12 exhibits metabolic stability and Caco-2 permeability, and good pharmacokinetic characteristics with good bioavailability (64%) and low clearance (0.16 L/hr/kg) in rats.

For research use only. We do not sell to patients.

  • Formula: C29H43NO4
  • Molecular Weight:469.66
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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