Amostomig
Based on 1 Customer Validation
Amostomig is a bispecific antibody targeting PD-L1/CD47, and the corresponding isotype control is: Human IgG1 lambda2, Isotype Control (HY-P990096). Amostomig can be used for cancer-related research.
For research use only. We do not sell to patients.
- Purity : 97.931%
- CAS No.: 2889449-09-4
- Molecular Weight:145.225 kDa
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Storage:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
Human IgG1 lambda2
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
CD274 & CD47
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Gene ID
Accession
Q9NZQ7 & Q61735-1
Conjugated
Unconjugated
Reconstitution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-lambda
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized CD47 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P78095) can bind Amostomig. The EC50 for this effect is 248.4 ng/mL. -
Immobilized PD-L1 Protein, Human (HEK293, HY-P73361) can bind Amostomig. The EC50 for this effect is 157.4 ng/mL. -
Flow cytometric analysis of 1X106 Jurkat cells labeling CD274 with Amostomig (HY-P990899, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 lambda2 Isotype Control (HY-P990096, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black). -
Flow cytometric analysis of 1X106 U937 cells labeling CD47 with Amostomig (HY-P990899, red). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 lambda2 Isotype Control (HY-P990096, blue) was used as the isotype control.
Chemical Information
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CAS No. 2889449-09-4
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Appearance Liquid
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Molecular Weight 145.225 kDa
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Color Colorless to off-white
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SMILES
[Amostomig]
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (274 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)