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Cat. No.: HY-157392

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hMAO-A-IN-1

hMAO-A-IN-1 (compound 8) is a potent hMAO-A inhibitor, with an IC₅₀ of 90 nM. hMAO-A-IN-1 can be used for the research of anxiety and depression.

For research use only. We do not sell to patients.

CAS No.: 1039315-88-2
Formula: C₁₇H₁₉ClN₂O
Molecular Weight:302.80

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

hMAO-A-IN-1 Chemical Structure

CAS No.: 1039315-88-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

hMAO-A-IN-1 (compound 8) is a potent hMAO-A inhibitor, with an IC₅₀ of 90 nM. hMAO-A-IN-1 can be used for the research of anxiety and depression^[1].

All Monoamine Oxidase Isoforms :

MAO-A
MAO-B

Chemical Information

CAS No. 1039315-88-2
Molecular Weight 302.80
Formula C₁₇H₁₉ClN₂O
SMILES

OCC1=CC=C(C=C1)N2CCN(CC2)C3=CC(Cl)=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. El-Halaby LO, et, al. Synthesis, in vitro, and in silico studies of new derivatives of diphenylpiperazine scaffold: A key substructure for MAO inhibition. Bioorg Chem. 2023 Dec 3:143:107011. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

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100 mg

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