HNF4 agonist 1
Based on 1 Customer Validation
HNF4 agonist 1 is a HNF4 agonist. HNF4 agonist 1 activates HNF4α and HNF4γ with EC50 values of 6 nM and 17 nM, respectively. HNF4 agonist 1 can be used in studies related to maturity-onset diabetes of the young type 1 (mody-1).
For research use only. We do not sell to patients.
- Purity: 99.37%
- Formula: C16H11ClO3
- Molecular Weight:286.71
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
HNF4 agonist 1 (Compound 46) binds to the lipid-free recombinant HNF4α LBD with a Kd value of 23 nM[1].
HNF4 agonist 1 activates HNF4α and HNF4γ in HEK293T cells via Gal4 hybrid reporter gene assay, with EC50 values of 6 nM and 17 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 286.71
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Formula C16H11ClO3
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Color White to off-white
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SMILES
OC(C1=C(C=CC(C#CC2=C(C=C(C=C2)C)Cl)=C1)O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)