Hydroxylamine (50% w/w in water)
Based on 2 publication(s) in Google Scholar
Hydroxylamine (50% w/w in water) is an inorganic highly reactive compound and antibacterial agent. Hydroxylamine (50% w/w in water) acutely activates the transport activity of GLUT1, inhibits Monoamine oxidase activity. Hydroxylamine (50% w/w in water) inhibits nitrite oxidizing bacteria. Hydroxylamine (50% w/w in water) activates glucose uptake. Hydroxylamine (50% w/w in water) can be used in the research of inflammatory diseases and allergies[1][2][3][4].
For research use only. We do not sell to patients.
- CAS No.: 7803-49-8
- Formula: H3NO
- Molecular Weight:33.03
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Storage:
Solution, -20°C, 2 years
Publications Citing Use of MedChemExpress (MCE) Hydroxylamine (50% w/w in water)
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Biological Activity
Description
IC50 & Target
[1]|
GLUT1 |
In Vitro
Hydroxylamine (1.0-20.0 mM; 0-20 min) acutely activates glucose uptake in L929 fibroblast cells in a dose-dependent manner[1].
Hydroxylamine (5.0 mM) has its glucose uptake activation in L929 fibroblast cells blocked by pretreatment with Iodoacetamide[1].
Hydroxylamine (1 mM; 1 h) potently inhibits purified monoamine oxidase from Escherichia coli K-12 with 99.8% inhibition[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 7803-49-8
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Appearance Liquid
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Molecular Weight 33.03
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Formula H3NO
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Color Colorless to light yellow
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SMILES
ON
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Publications (2)
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Journal Impact Factor
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Most Recent
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Research (Wash D C)
EVA1A Regulates Hepatic Lipid Homeostasis by Modulating CD36 Expression and Its Palmitoylation. [Abstract]2025 Nov 25:8:1001. PMID: 41306774 -
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
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Data Sheet (270 KB)
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SDS (926 KB)
- English - EN (926 KB)
- Français - FR (926 KB)
- Deutsch - DE (926 KB)
- Norwegian - NO (926 KB)
- Español - ES (926 KB)
- Swedish - SV (926 KB)
- Italian - IT (926 KB)
- Korean - KR (926 KB)
- Portuguese - PT (926 KB)
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Handling Instructions (2659 KB)
References
[1]. Kataoka H, et al. Anti-inflammatory and anti-allergic activities of hydroxylamine and related compounds. Biol Pharm Bull. 2002 Nov;25(11):1436-41. [Content Brief]
[2]. Zhang R, et al. Both hydroxylamine and nitroxide protect cardiomyocytes from oxidative stress. Free Radic Biol Med. 1998 Jan 1;24(1):66-75. [Content Brief]
[3]. Soler-Jofra A, et al. Hydroxylamine and the nitrogen cycle: A review. Water Res. 2021 Feb 15;190:116723. [Content Brief]
[4]. Louters LL, et al. Hydroxylamine acutely activates glucose uptake in L929 fibroblast cells. Biochimie. 2013;95(4):787-792. [Content Brief]
[5]. Roh JH, et al. Purification, characterization, and crystallization of monoamine oxidase from Escherichia coli K-12. Biosci Biotechnol Biochem. 1994;58(9):1652-1656. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)