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Cat. No.: HY-158198

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PRXS571

PRXS571 is a potent modulator of the neuronal integrated stress response (ISR) and can be used in neural-related research.

For research use only. We do not sell to patients.

CAS No.: 2396759-31-0
Formula: C₂₃H₂₃Cl₂FN₄O₃
Molecular Weight:493.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

PRXS571 Chemical Structure

CAS No.: 2396759-31-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

PRXS571 is a potent modulator of the neuronal integrated stress response (ISR) and can be used in neural-related research^[1].

IC₅₀ & Target

integrated stress response (ISR)^[1]

Chemical Information

CAS No. 2396759-31-0
Molecular Weight 493.36
Formula C₂₃H₂₃Cl₂FN₄O₃
SMILES

FC(C=C1OC[C@H](O)CN(CC2)CCN2NC(C3=NC4=C(C=C(C=C4)Cl)C=C3)=O)=C(C=C1)Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Marlin E, et al. Pharmacological inhibition of the integrated stress response accelerates disease progression in an amyotrophic lateral sclerosis mouse model. Br J Pharmacol. 2024 Feb;181(3):495-508. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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