country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-189072

Copy Link Print Information

Insecticidal agent 39

Insecticidal agent 39 (compound I ai) is a potent insecticide that targets Ryanodine Receptor (RyR). The LC₅₀ of Insecticidal agent 39 against M. separata is 0.26 mg/L. Insecticidal agent 39 specifically binds to and activates RyR, inducing the release of Ca²⁺ from the sarcoplasmic reticulum into the cytoplasm, which leads to sustained muscle contraction and eventual paralysis and death of the pest. Insecticidal agent 39 can be used in studies related to lepidopteran pest infestation.

For research use only. We do not sell to patients.

Formula: C₂₄H₁₈BrCl₂N₃O₂
Molecular Weight:531.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Insecticidal agent 39 Chemical Structure

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Calcium Channel Isoforms :

In Vitro

Insecticidal agent 39 (compound I ai) binds to the Mythimna separata ryanodine receptor (MsRyR) with a binding energy of 8.1 kcal/mol. It shares the same binding pocket as Chlorantraniliprole (HY-112820) and forms key hydrogen bonds with ASP-4901 and LYS-4652^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Insecticidal agent 39 (compound I ai) (oral exposure via treated maize leaves, single administration) exhibits potent insecticidal activity against Mythimna separata, Plutella xylostella and Spodoptera frugiperda, with an LC₅₀ of 0.26 mg/L against Mythimna separata^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 531.23
Formula C₂₄H₁₈BrCl₂N₃O₂
SMILES

ClC1=C(N2C(C=CC(Br)=C3)=C3C=C2C(NC4=C(C(NC)=O)C=C(Cl)C=C4C)=O)C=CC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Duan J, et al. Discovery of Substituted N-Arylindole Diamides as Insecticidal Candidates Targeting Ryanodine Receptor. Journal of agricultural and food chemistry. 2026 Aug 12;74(31):24115-24123.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote