2. Immunology/Inflammation
  3. Cyclic GMP-AMP Synthase
  4. Iptocigistat

Iptocigistat (Iptocigistatum) is a cyclic GMP-AMP synthase (cGAS) inhibitor. Iptocigistat prevents excessive immune responses. Iptocigistat can be used to study inflammation-related autoimmune diseases.

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Iptocigistat

Iptocigistat Chemical Structure

CAS No. : 3047739-67-0

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Iptocigistat Related Antibodies

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Description

Iptocigistat (Iptocigistatum) is a cyclic GMP-AMP synthase (cGAS) inhibitor. Iptocigistat prevents excessive immune responses. Iptocigistat can be used to study inflammation-related autoimmune diseases[1].

In Vitro

Iptocigistat (Compound 10) inhibits the activity of human guanylate-adenylate cyclase in a cell-free Kinase-Glo assay, with an IC50 ranging from ≥0.005 μM to <0.02 μM[1].
Iptocigistat inhibits the activity of human guanylate-adenylate synthase in cell-free LCMS assays, with an IC50 of ≥0.005 μM and <0.02 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Iptocigistat Related Antibodies
Molecular Weight

450.47

Formula

C18H22N6O6S
CAS No.
SMILES

O=C1OC(C(NC2=NN=C(N3N=CC=C3C)S2)=O)=CC(NC(COC)COC)=C1OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Iptocigistat Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Iptocigistat3047739-67-0IptocigistatumCyclic GMP-AMP SynthasecGAShuman cyclic GMP-AMP synthaseinflammatory componenthuman cellsautoimmune conditionshcGASInhibitorinhibitorinhibit

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