Schip1 - schwannomin interacting protein 1 Gene

Also Known as Nf2ip; Schip-1

Species: Mus musculus

Gene Type: protein coding

Gene ID: 30953

Summary

Predicted to enable protein homodimerization activity. Acts upstream of or within several processes, including animal organ development; face morphogenesis; and fibroblast migration. Predicted to be located in cytoplasm. Predicted to be active in cell junction and plasma membrane. Is expressed in alimentary system; aorta; genitourinary system; nervous system; and sensory organ. Orthologous to human SCHIP1 (schwannomin interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Schip1 Products (5)

mRNA	Protein	Name
NM_001113420.1	NP_001106891.1	schwannomin-interacting protein 1 isoform b
NM_001113421.1	NP_001106892.1	schwannomin-interacting protein 1 isoform c
NM_001282044.1	NP_001268973.1	schwannomin-interacting protein 1 isoform e
NM_001282045.1	NP_001268974.1	schwannomin-interacting protein 1 isoform e
NM_013928.5	NP_038956.2	schwannomin-interacting protein 1 isoform d

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	10669747	MGI

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within estrogen metabolic process	IGI IGI: Inferred from genetic interaction	19056881	MGI
acts upstream of or within excretion	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within face morphogenesis	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within female gonad development	IGI IGI: Inferred from genetic interaction	19056881	MGI
acts upstream of or within fibroblast migration	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within kidney development	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within luteinization	IGI IGI: Inferred from genetic interaction	19056881	MGI
acts upstream of or within platelet-derived growth factor receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within post-embryonic development	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within roof of mouth development	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within skeletal system morphogenesis	IMP IMP: Inferred from mutant phenotype	17143286	MGI
acts upstream of or within smooth muscle tissue development	IMP IMP: Inferred from mutant phenotype	17143286	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
schwannomin-interacting protein 1	neurofibromatosis 2 interacting protein

Schip1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Cross	Schip1	P0DPB4	NF2	Homo sapiens	P35240	Pull Down	10669747

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12510	SCHIP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Schip1	NCBI	NCBI:29970