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Cat. No.: HY-10544R

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Tegobuvir (Standard)

(Synonyms: GS 333126 (Standard); GS-9190 (Standard))

Tegobuvir (Standard) is the analytical standard of Tegobuvir (HY-10544). This product is intended for research and analytical applications. Tegobuvir is a specific, covalent inhibitor of the HCV NS5B polymerase.

For research use only. We do not sell to patients.

CAS No.: 1000787-75-6
Formula: C₂₅H₁₄F₇N₅
Molecular Weight:517.40

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Tegobuvir (Standard) Chemical Structure

CAS No.: 1000787-75-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information
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- Application
Chemical Information
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 1000787-75-6
Molecular Weight 517.40
Formula C₂₅H₁₄F₇N₅
SMILES

FC1=CC=CC=C1C2=NC3=CN(CC4=NN=C(C5=CC=C(C(F)(F)F)C=C5C(F)(F)F)C=C4)C=CC3=N2
Synonyms

GS 333126 (Standard); GS-9190 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Bae AS, et al. Allele-specific real-time PCR system for detection of subpopulations of genotype 1a and 1b hepatitis C NS5B Y448H mutant viruses in clinical samples. J Clin Microbiol. 2011 Sep;49(9):3168-74. [Content Brief]

[2]. Hebner CM, et al. The HCV non-nucleoside inhibitor Tegobuvir utilizes a novel mechanism of action to inhibit NS5B polymerase function. PLoS One. 2012;7(6):e39163. [Content Brief]

[3]. Wong KA, et al. Tegobuvir (GS-9190) potency against HCV chimeric replicons derived from consensus NS5B sequences from genotypes 2b, 3a, 4a, 5a, and 6a. Virology. 2012 Jul 20;429(1):57-62. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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