Ethenzamide
Based on 1 Customer Validation
2-Ethoxybenzamide (Ethenzamide) is a nonsteroidal anti-inflammatory agent that shows analgesic and antipyretic effects. 2-Ethoxybenzamide induces melanin synthesis via cAMP response element-binding protein (CREB) phosphorylation. 2-Ethoxybenzamide can be used in the research of hypopigmentation and inflammation-related diseases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.82%
- CAS 番号: 938-73-8
- 分子式: C9H11NO2
- 分子量:165.19
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
2-Ethoxybenzamide (125-500 μM; 24-72 h) can increase the ROS level, enhance the expression of melanogenesis-related genes, and promote melanin synthesis in B16F1 murine melanoma cells. The mechanism involves the phosphorylation of ERK/CREB[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:B16F1 melanoma cells
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Concentration:0, 125, 250 and 500 μM
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Incubation Time:72 h
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Result:Significantly increased the level of tyrosinase.
Slightly increased TRP-1 protein level and did not affect TRP-2 expression.
化学情報
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CAS 番号 938-73-8
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性状 Solid
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分子量 165.19
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分子式 C9H11NO2
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Color White to off-white
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SMILES
O=C(N)C1=CC=CC=C1OCC
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別名
2-Ethoxybenzamide; 2-エトキシベンズアミド
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
溶剤 & 溶解度
DMSO : ≥ 47 mg/mL (284.52 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.0536 mL | 30.2682 mL | 60.5364 mL | 151.3409 mL |
| 5 mM | 1.2107 mL | 6.0536 mL | 12.1073 mL | 30.2682 mL | |
| 10 mM | 0.6054 mL | 3.0268 mL | 6.0536 mL | 15.1341 mL | |
| 15 mM | 0.4036 mL | 2.0179 mL | 4.0358 mL | 10.0894 mL | |
| 20 mM | 0.3027 mL | 1.5134 mL | 3.0268 mL | 7.5670 mL | |
| 25 mM | 0.2421 mL | 1.2107 mL | 2.4215 mL | 6.0536 mL | |
| 30 mM | 0.2018 mL | 1.0089 mL | 2.0179 mL | 5.0447 mL | |
| 40 mM | 0.1513 mL | 0.7567 mL | 1.5134 mL | 3.7835 mL | |
| 50 mM | 0.1211 mL | 0.6054 mL | 1.2107 mL | 3.0268 mL | |
| 60 mM | 0.1009 mL | 0.5045 mL | 1.0089 mL | 2.5223 mL | |
| 80 mM | 0.0757 mL | 0.3784 mL | 0.7567 mL | 1.8918 mL | |
| 100 mM | 0.0605 mL | 0.3027 mL | 0.6054 mL | 1.5134 mL |
2-Ethoxybenzamide 関連分類
HY-B1428 関連分類
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