D2343
D2343 is a β2-adrenoceptor agonist and also is an α1- adrenoceptor inhibitor.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 72734-63-5
- 分子式: C20H27NO3
- 分子量:329.43
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Adrenergic Receptor アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
体外実験
D2343 is a compound with about the same beta 2-adrenoceptor-agonist effect as Terbutaline and exhibiting in addition an alpha 1-receptor inhibitory activity[1]. The beta 2-agonistic and alpha 1-antagonistic drug D2343 inhibits the evoked contractions in a concentration related fashion with 50% effect at 9.6 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 72734-63-5
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分子量 329.43
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分子式 C20H27NO3
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SMILES
OC(C1=CC=C(O)C=C1)CNC(C)(C)CCC2=C(C=CC=C2)OC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Olsson OA, et al. The effects in myometrial preparations of D2343, a beta 2-adrenoceptor agonist possessing alpha 1-receptor blocking qualities. Acta Pharmacol Toxicol (Copenh). 1984 Nov;55(5):391-7. [Content Brief]
[2]. Olsson OA, et al. The effect of D2343 in transmurally stimulated rabbit isthmus muscle. Acta Pharmacol Toxicol (Copenh). 1985 May;56(5):427-30. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)