IX 207-887
Based on 1 Customer Validation
IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.96%
- CAS 番号: 98320-39-9
- 分子式: C16H12O3S
- 分子量:284.33
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
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IL-2 |
IL-1 |
IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 98320-39-9
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性状 Solid
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分子量 284.33
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分子式 C16H12O3S
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Color Light yellow to yellow
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SMILES
OC(/C=C1C2=C(SC=C2)C(OC)=CC3=C\1C=CC=C3)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (351.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5170 mL | 17.5852 mL | 35.1704 mL | 87.9260 mL |
| 5 mM | 0.7034 mL | 3.5170 mL | 7.0341 mL | 17.5852 mL | |
| 10 mM | 0.3517 mL | 1.7585 mL | 3.5170 mL | 8.7926 mL | |
| 15 mM | 0.2345 mL | 1.1723 mL | 2.3447 mL | 5.8617 mL | |
| 20 mM | 0.1759 mL | 0.8793 mL | 1.7585 mL | 4.3963 mL | |
| 25 mM | 0.1407 mL | 0.7034 mL | 1.4068 mL | 3.5170 mL | |
| 30 mM | 0.1172 mL | 0.5862 mL | 1.1723 mL | 2.9309 mL | |
| 40 mM | 0.0879 mL | 0.4396 mL | 0.8793 mL | 2.1982 mL | |
| 50 mM | 0.0703 mL | 0.3517 mL | 0.7034 mL | 1.7585 mL | |
| 60 mM | 0.0586 mL | 0.2931 mL | 0.5862 mL | 1.4654 mL | |
| 80 mM | 0.0440 mL | 0.2198 mL | 0.4396 mL | 1.0991 mL | |
| 100 mM | 0.0352 mL | 0.1759 mL | 0.3517 mL | 0.8793 mL |