B26 peptoid
B26 peptoid is a ptoid antibiotic. B26 peptoid exhibits excellent broad-spectrum activity and high selectivity toward a panel of Gram-positive and Gram-negative bacterial strains. B26 peptoid disrupts bacterial membranes and has bactericidal activity. B26 peptoid shows low propensity for bacterial drug resistance. B26 peptoid can be used for the research of bacterial infection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C58H114N12O8
- 分子量:1107.60
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Antibiotic アイソフォーム固有の製品をすべて表示
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生物活性
B26 peptoid (16 h) potently inhibits the growth of vancomycin-resistant E. faecalis, methicillin-resistant S. aureus, methicillin-resistant S. epidermidis, E. coli, P. aeruginosa, and K. pneumoniae with MIC values ranging from <3 μg/mL[1].
B26 peptoid (2× MIC; 2 h) disrupts the cell membranes of methicillin-resistant S. aureus and E. coli, allowing propidium iodide to enter and stain bacterial cells[1].
B26 peptoid (2× MIC; 2 h) causes severe membrane disruption and cellular damage in methicillin-resistant S. aureus and E. coli, as visualized by transmission electron microscopy[1].
B26 peptoid maintains stable, consistent antimicrobial activity against methicillin-resistant S. aureus over 14 serial passages, with no significant development of bacterial drug resistance[1].
B26 peptoid (12 μg/mL; 0-2 h) rapidly kills methicillin-resistant S. aureus and E. coli[1].
B26 peptoid (1 h) has low hemolytic toxicity toward human red blood cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:methicillin-resistant S. aureus; E. col
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Concentration:12 μg/mL
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Incubation Time:0-2 h
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Result:Killed methicillin-resistant S. aureus within 2 hours and E. coli within 1 hour.
化学情報
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分子量 1107.60
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分子式 C58H114N12O8
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)