Bis-PEG14-acid
Based on 1 Customer Validation
Bis-PEG14-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- 分子式: C32H62O18
- 分子量:734.82
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保管条件:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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性状 Solid-Liquid Mixture
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分子量 734.82
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分子式 C32H62O18
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Color White to off-white
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SMILES
OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
H2O : 350 mg/mL (476.31 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.3609 mL | 6.8044 mL | 13.6088 mL | 34.0219 mL |
| 5 mM | 0.2722 mL | 1.3609 mL | 2.7218 mL | 6.8044 mL | |
| 10 mM | 0.1361 mL | 0.6804 mL | 1.3609 mL | 3.4022 mL | |
| 15 mM | 0.0907 mL | 0.4536 mL | 0.9073 mL | 2.2681 mL | |
| 20 mM | 0.0680 mL | 0.3402 mL | 0.6804 mL | 1.7011 mL | |
| 25 mM | 0.0544 mL | 0.2722 mL | 0.5444 mL | 1.3609 mL | |
| 30 mM | 0.0454 mL | 0.2268 mL | 0.4536 mL | 1.1341 mL | |
| 40 mM | 0.0340 mL | 0.1701 mL | 0.3402 mL | 0.8505 mL | |
| 50 mM | 0.0272 mL | 0.1361 mL | 0.2722 mL | 0.6804 mL | |
| 60 mM | 0.0227 mL | 0.1134 mL | 0.2268 mL | 0.5670 mL | |
| 80 mM | 0.0170 mL | 0.0851 mL | 0.1701 mL | 0.4253 mL | |
| 100 mM | 0.0136 mL | 0.0680 mL | 0.1361 mL | 0.3402 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.