Bromo-PEG5-azide
Based on 1 Customer Validation
Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Bromo-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 1402411-90-8
- 分子式: C12H24BrN3O5
- 分子量:370.24
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保管条件:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1402411-90-8
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性状 Liquid
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分子量 370.24
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分子式 C12H24BrN3O5
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Color Colorless to light yellow
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SMILES
BrCCOCCOCCOCCOCCOCCN=[N+]=[N-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
DMSO : 100 mg/mL (270.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (265 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7010 mL | 13.5048 mL | 27.0095 mL | 67.5238 mL |
| 5 mM | 0.5402 mL | 2.7010 mL | 5.4019 mL | 13.5048 mL | |
| 10 mM | 0.2701 mL | 1.3505 mL | 2.7010 mL | 6.7524 mL | |
| 15 mM | 0.1801 mL | 0.9003 mL | 1.8006 mL | 4.5016 mL | |
| 20 mM | 0.1350 mL | 0.6752 mL | 1.3505 mL | 3.3762 mL | |
| 25 mM | 0.1080 mL | 0.5402 mL | 1.0804 mL | 2.7010 mL | |
| 30 mM | 0.0900 mL | 0.4502 mL | 0.9003 mL | 2.2508 mL | |
| 40 mM | 0.0675 mL | 0.3376 mL | 0.6752 mL | 1.6881 mL | |
| 50 mM | 0.0540 mL | 0.2701 mL | 0.5402 mL | 1.3505 mL | |
| 60 mM | 0.0450 mL | 0.2251 mL | 0.4502 mL | 1.1254 mL | |
| 80 mM | 0.0338 mL | 0.1688 mL | 0.3376 mL | 0.8440 mL | |
| 100 mM | 0.0270 mL | 0.1350 mL | 0.2701 mL | 0.6752 mL |
Bromo-PEG5-azide 関連分類
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