CCG-232601
Based on 1 Customer Validation
CCG-232601 (compound 8f) is a potent and orally active Rho/MRTF/SRF transcriptional pathway inhibitor. CCG-232601 inhibits the development of Bleomycin-induced dermal fibrosis in mice. CCG-232601 has the potential for the research of antifibrotic for systemic scleroderma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.00%
- CAS 番号: 1922099-21-5
- 分子式: C24H20ClF2N3O2
- 分子量:455.88
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
CCG-232601 inhibits SRE.L activity with an IC50 of 0.55 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1922099-21-5
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性状 Solid
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分子量 455.88
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分子式 C24H20ClF2N3O2
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Color White to off-white
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SMILES
O=C(C1CN(C(C2=CC=CC(C3=CC=NC=C3)=C2)=O)CC(F)(F)C1)NC4=CC=C(Cl)C=C4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 40 mg/mL (87.74 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1936 mL | 10.9678 mL | 21.9356 mL | 54.8390 mL |
| 5 mM | 0.4387 mL | 2.1936 mL | 4.3871 mL | 10.9678 mL | |
| 10 mM | 0.2194 mL | 1.0968 mL | 2.1936 mL | 5.4839 mL | |
| 15 mM | 0.1462 mL | 0.7312 mL | 1.4624 mL | 3.6559 mL | |
| 20 mM | 0.1097 mL | 0.5484 mL | 1.0968 mL | 2.7419 mL | |
| 25 mM | 0.0877 mL | 0.4387 mL | 0.8774 mL | 2.1936 mL | |
| 30 mM | 0.0731 mL | 0.3656 mL | 0.7312 mL | 1.8280 mL | |
| 40 mM | 0.0548 mL | 0.2742 mL | 0.5484 mL | 1.3710 mL | |
| 50 mM | 0.0439 mL | 0.2194 mL | 0.4387 mL | 1.0968 mL | |
| 60 mM | 0.0366 mL | 0.1828 mL | 0.3656 mL | 0.9140 mL | |
| 80 mM | 0.0274 mL | 0.1371 mL | 0.2742 mL | 0.6855 mL |
CCG-232601 関連分類
HY-111432 関連分類
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