country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-106650

Copy Link Print Information

CMDA

CMDA is a prodrug that can release cytotoxic molecules under the action of CPG2. CMDA can be used for cancer research.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 122665-73-0
分子式: C₁₇H₂₃ClN₂O₈S
分子量:450.89

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

CMDA 構造式

CAS 番号: 122665-73-0

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

CMDA is a prodrug that can release cytotoxic molecules under the action of CPG2. CMDA can be used for cancer research^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
LoVo	IC₅₀	>500 μM Compound: 1	Inhibitory concentration was evaluated against colorectal tumar cell line LoVo Inhibitory concentration was evaluated against colorectal tumar cell line LoVo	[PMID: 8676345]
LS174T	IC₅₀	>800200 μM Compound: 40	Compound was evaluated for its cytotoxicity without carboxypeptidase G2 in the colorectal cell line LS174T for 1 hour Compound was evaluated for its cytotoxicity without carboxypeptidase G2 in the colorectal cell line LS174T for 1 hour	[PMID: 8057284]
LS174T	IC₅₀	200 μM Compound: 40	Compound was evaluated for its cytotoxicity with carboxypeptidase G2 in the colorectal cell line LS174T for 1 hour Compound was evaluated for its cytotoxicity with carboxypeptidase G2 in the colorectal cell line LS174T for 1 hour	[PMID: 8057284]
WiDr	IC₅₀	100 μM Compound: CMDA	Compound was tested for cytotoxicity in WiDr cells engineered for stable expression of surface-tethered CPG2 Compound was tested for cytotoxicity in WiDr cells engineered for stable expression of surface-tethered CPG2	[PMID: 12699387]
WiDr	IC₅₀	3230 μM Compound: CMDA	Compound was tested for cytotoxicity in WiDr cells engineered for stable expression of beta-galactosidase Compound was tested for cytotoxicity in WiDr cells engineered for stable expression of beta-galactosidase	[PMID: 12699387]

化学情報

CAS 番号 122665-73-0
分子量 450.89
分子式 C₁₇H₂₃ClN₂O₈S
SMILES

CS(OCCN(C1=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C1)CCCl)(=O)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (264 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Yu T, et al. Development of ZD2767P-carboxypeptidase G2-ultrasound therapy against cisplatin-resistant cancer. Front Oncol. 2023 May 18;13:1151613. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ