Collinin
Collinin is a anti-tubercular agent, it can be isolated from leaves of Z. schinifolium. Collinin has an excellent anti-tuberculosis effect against multidrug-resistant (MDR), extensively drug-resistant (XDR) strains.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 34465-83-3
- 分子式: C20H24O4
- 分子量:328.40
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
5.9 μM
Compound: collinin
|
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production
Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production
|
[PMID: 28844340] |
Collinin significantly inhibits the growth of MDR and XDR M. tuberculosis in the culture broth with 50% minimum inhibitory concentrations (MIC50s) of 3.13-6.25 µg/mL[1].
Collinin inhibits the growth of intracellular drug-susceptible and drug-resistant tuberculosis in Raw264.7 and A549 cells with MIC50s of 6.25-12.50 µg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 34465-83-3
-
分子量 328.40
-
分子式 C20H24O4
-
SMILES
O=C1C=CC2=CC=C(OC/C=C(C)/CC/C=C(C)/C)C(OC)=C2O1
-
Structure Classification
-
Initial Source
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)