Cristacarpin
Cristacarpin can be extracted from the stem bark of Erythrina suberosa, promotes endoplasmic reticulum (ER) stress, leading to sublethal reactive oxygen species (ROS) production and ultimately cell death through senescence.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 74515-47-2
- 分子式: C21H22O5
- 分子量:354.40
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
3.36 μM
Compound: 8
|
Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 28189086] |
| CHO | IC50 |
>20 μM
Compound: 2
|
Cytotoxicity against CHO cells
Cytotoxicity against CHO cells
|
[PMID: 8277323] |
| CHO | IC50 |
4 μM
Compound: 2
|
Cytotoxicity against p-glycoprotein overexpressing CHO cells
Cytotoxicity against p-glycoprotein overexpressing CHO cells
|
[PMID: 8277323] |
| P388 | IC50 |
>10 μM
Compound: 2
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 8277323] |
化学情報
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CAS 番号 74515-47-2
-
分子量 354.40
-
分子式 C21H22O5
-
SMILES
O[C@]12[C@](OC3=C(C/C=C(C)\C)C(OC)=CC=C32)([H])C4=CC=C(O)C=C4OC1
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別名
Erythrabyssin I; Erythrabissin I
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)