Dienone B
Based on 1 Customer Validation
Dienone B is a marine algicide with antibiotic activity against both Gram-positive and Gram-negative marine bacteria.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 97.15%
- CAS 番号: 17194-81-9
- 分子式: C8H7Br2NO3
- 分子量:324.95
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa S3 | IC50 |
1.5 μM
Compound: 2
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Dose enhancement factor, ratio of IC50 for human HeLaS3 cells after 4 days to IC50 for buthionine sulfoximine-pretreated human HeLaS3 cells after 4 days by MTT assay
Dose enhancement factor, ratio of IC50 for human HeLaS3 cells after 4 days to IC50 for buthionine sulfoximine-pretreated human HeLaS3 cells after 4 days by MTT assay
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[PMID: 8786366] |
| HeLa S3 | IC50 |
10.4 μM
Compound: 2
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Cytotoxicity against buthionine sulfoximine-pretreated human HeLaS3 cells after 4 days by MTT assay
Cytotoxicity against buthionine sulfoximine-pretreated human HeLaS3 cells after 4 days by MTT assay
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[PMID: 8786366] |
| HeLa S3 | IC50 |
15.6 μM
Compound: 2
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Cytotoxicity against human HeLaS3 cells after 4 days by MTT assay
Cytotoxicity against human HeLaS3 cells after 4 days by MTT assay
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[PMID: 8786366] |
| HeLa S3 | IC50 |
15.7 μM
Compound: 2
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Cytotoxicity against buthionine sulfoximine-pretreated human HeLaS3 cells after 2 hrs by MTT assay
Cytotoxicity against buthionine sulfoximine-pretreated human HeLaS3 cells after 2 hrs by MTT assay
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[PMID: 8786366] |
| HeLa S3 | IC50 |
2 μM
Compound: 2
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Dose enhancement factor, ratio of IC50 for human HeLaS3 cells after 2 hrs to IC50 for buthionine sulfoximine-pretreated human HeLaS3 cells after 2 hrs by MTT assay
Dose enhancement factor, ratio of IC50 for human HeLaS3 cells after 2 hrs to IC50 for buthionine sulfoximine-pretreated human HeLaS3 cells after 2 hrs by MTT assay
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[PMID: 8786366] |
| HeLa S3 | IC50 |
31.9 μM
Compound: 2
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Cytotoxicity against human HeLaS3 cells after 2 hrs by MTT assay
Cytotoxicity against human HeLaS3 cells after 2 hrs by MTT assay
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[PMID: 8786366] |
| HeLa S3 | IC50 |
58 μM
Compound: 2
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Cytotoxicity against human HeLaS3 cells after 2 weeks by clonogenic assay
Cytotoxicity against human HeLaS3 cells after 2 weeks by clonogenic assay
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[PMID: 8786366] |
化学情報
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CAS 番号 17194-81-9
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性状 Solid
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分子量 324.95
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分子式 C8H7Br2NO3
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Color White to off-white
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SMILES
O=C(CC1(C=C(C(C(Br)=C1)=O)Br)O)N
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別名
Dibromoverongiaquinol
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Initial Source
Verongia aerophoba
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 25 mg/mL (76.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
純度とドキュメンテーション
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データシート (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0774 mL | 15.3870 mL | 30.7740 mL | 76.9349 mL |
| 5 mM | 0.6155 mL | 3.0774 mL | 6.1548 mL | 15.3870 mL | |
| 10 mM | 0.3077 mL | 1.5387 mL | 3.0774 mL | 7.6935 mL | |
| 15 mM | 0.2052 mL | 1.0258 mL | 2.0516 mL | 5.1290 mL | |
| 20 mM | 0.1539 mL | 0.7693 mL | 1.5387 mL | 3.8467 mL | |
| 25 mM | 0.1231 mL | 0.6155 mL | 1.2310 mL | 3.0774 mL | |
| 30 mM | 0.1026 mL | 0.5129 mL | 1.0258 mL | 2.5645 mL | |
| 40 mM | 0.0769 mL | 0.3847 mL | 0.7693 mL | 1.9234 mL | |
| 50 mM | 0.0615 mL | 0.3077 mL | 0.6155 mL | 1.5387 mL | |
| 60 mM | 0.0513 mL | 0.2564 mL | 0.5129 mL | 1.2822 mL |
Dienone B 関連分類
HY-121922 関連分類
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