DOPE-PEG2000-MTP
DOPE-PEG2000-MTP (DOPE-PEG2000-Mal-Cys-ASSLNIA) is an amphiphilic lipid-PEG-peptide conjugate consisting of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the MTP (mitochondria-targeting peptide). MTP peptide functions as a mitochondria-directed targeting ligand. DOPE-PEG2000-MTP is designed for functionalizing nanocarriers to deliver drugs specifically to mitochondria.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
生物活性
製品説明
体外実験
DOPE-PEG2000-MTP: functionalization of liposomes and nanoparticles for mitochondria-targeted drug delivery, particularly for pro-apoptotic agents, reactive oxygen species (ROS) modulators, and mitochondria-damaging therapeutics in cancer therapy.
Structural composition:
(1) DOPE; a fusogenic phospholipid with two unsaturated oleoyl chains that anchors into lipid bilayers and facilitates membrane fusion and endosomal escape;
(2) PEG2000; a hydrophilic polymer that provides steric stabilization, reduces protein adsorption and RES clearance, and extends circulation time;
(3) MTP peptide; a mitochondria-targeting peptide that exploits mitochondrial membrane potential to accumulate in mitochondria, enabling selective delivery of cargo to this organelle for modulating mitochondrial function and inducing apoptosis in target cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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SMILES
[DOPE-PEG2000-MTP]
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別名
DOPE-PEG2000-Mal-Cys-ASSLNIA
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DOPE-PEG2000-MTP 関連分類
HY-187409A 関連分類
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