DSPE-PEG5000-M2pep
DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY is a PEG compound which composed of DSPE and a M2-polarized macrophages targeting peptide (M2pep, YEQDPWGVKWWY). M2pep is conjugated to a proapoptotic peptide as monovalent or multivalent ligands to concentrate the toxic effect of the peptide to M2 macrophages. DSPE-PEG5000-Mal-Cys-YEQDPWGVKWWY can be used for drug delivery.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
DSPE-PEG-Mal-Cys-YEQDPWGVKWWY consists of three parts: a hydrophobic 1,2-distearate-sn-glycerol-3-phosphate ethanolamine (DSPE), a hydrophilic PEG chain, and a terminally modified M2pep targeting peptide (YEQDPWGVKWWY). This amphiphilic structure facilitates its embedding in the lipid bilayer while exposing the M2pep peptide on its outer surface, enabling the recognition of surface markers on M2 macrophages. It is noteworthy that the choice of PEG chain length (e.g., PEG2000) significantly affects blood circulation time and steric hindrance effects, requiring optimization based on specific experimental models.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
SMILES
[Mal-Cys-YEQDPWGVKWWY]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DSPE-PEG5000-M2pep 関連分類
HY-172273B 関連分類
Powered by Bioz