Epanorin
Epanorin is a secondary metabolite of the Acarospora lichenic species Epanorin can inhibit cancer cells proliferation, ROS production and induce G0/G1 phase arrest. Epanorin shows antibacterial activity. Epanorin can be used for the researches of cancer and infection, such as breast cancer and S. pneumonia infection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 18463-10-0
- 分子式: C25H25NO6
- 分子量:435.47
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Epanorin shows potent inhibitory activity against breast cancer cell line (up to 80%) and moderate inhibitory activity for meningioma (up to 40%)[1].
Epanorin (28 μM) reduces cell colonies in MCF-7 cells[1].
Epanorin (28 μM, 48 h) reduces ROS production in Doxorubicin (HY-15142A)-induced MCF-7 cells[1].
Epanorin (28 μM, 48 h) induces G0/G1 phase arrest in MCF-7 cells[1].
Epanorin (28 μM, 12 h) does not induce detectable DNA fragmentation in MCF-7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MCF-7 cells
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Concentration:28 μM
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Incubation Time:48 h
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Result:Increased the cells on G0 phase.
Reduced cells on S phase.
化学情報
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CAS 番号 18463-10-0
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分子量 435.47
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分子式 C25H25NO6
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SMILES
COC([C@H](CC(C)C)NC(/C(C1=CC=CC=C1)=C2C(O)=C(C3=CC=CC=C3)C(O/2)=O)=O)=O
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Structure Classification
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Initial Source
Acarospora schleicheri
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)