Ppp1cc - protein phosphatase 1 catalytic subunit gamma Gene

Also Known as PP-1G; Ppp1cc1

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 24669

Summary

Enables several functions, including lamin binding activity; protein C-terminus binding activity; and protein Phosphatase 1 binding activity. Involved in positive regulation of glial cell proliferation. Acts upstream of or within neuron differentiation. Located in cytoplasm and dendritic spine. Is active in glutamatergic synapse; postsynapse; and presynapse. Biomarker of congestive heart failure. Orthologous to human PPP1CC (protein Phosphatase 1 catalytic subunit gamma). [provided by Alliance of Genome Resources, Apr 2022]

Ppp1cc Products (2)

mRNA Protein Name
NM_001270983.1 NP_001257912.1 serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform 2
NM_022498.2 NP_071943.1 serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables lamin binding IPI
IPI: Inferred from physical interaction
17683050 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10391935 RGD
enables protein domain specific binding IMP
IMP: Inferred from mutant phenotype
18216290 RGD
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
18216290 RGD
enables protein phosphatase 1 binding IPI
IPI: Inferred from physical interaction
9275233 RGD
enables protein phosphatase binding IDA
IDA: Inferred from direct assay
18216290 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
10504266 RGD
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within neuron differentiation IDA
IDA: Inferred from direct assay
17202132 RGD
involved in positive regulation of glial cell proliferation IMP
IMP: Inferred from mutant phenotype
29033188 RGD
Cellular Component GO Annotation Evidence 参考文献 由来
located in dendritic spine IDA
IDA: Inferred from direct assay
7724573 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
7724573 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
7724573 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
7724573 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein phosphatase PP1-gamma catalytic subunit

  • protein phosphatase 1, catalytic subunit, gamma isozyme

  • protein phosphatase 1C catalytic subunit

  • protein serine-threonine phosphatase catalytic subunit PP-1b

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS10975 PPP1CC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19803 Ppp1cc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26299 Ppp1cc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Ppp1cc NCBI NCBI:5501