RGS13 - regulator of G protein signaling 13 Gene
生物種: Homo sapiens
About RGS13
This gene has 4 transcripts (splice variants), 262 orthologues and 23 paralogues. Biased expression in lymph node (RPKM 52.7), appendix (RPKM 9.2) and 2 other tissues.
Summary
The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008]
RGS13 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_002927.5 | NP_002918.1 | regulator of G-protein signaling 13 |
| NM_144766.3 | NP_658912.1 | regulator of G-protein signaling 13 |
| Molecular Function GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
RGS13 Protein Structure
RGS: Regulator of G protein signaling domain (34 - 149)
- 0
- 100
- 159 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
regulator of G-protein signaling 13 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| 製品番号 | 製品名 |
製品効果
|
純度 |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS11906 | RGS13 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS11912 | RGS18 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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