Halofenozide
Based on 1 Customer Validation
Halofenozide (RH-0345) is an ecdysteroid agonist. RH-0345 belongs to a new group of insect growth regulators (IGRs) with a benzoylhydrazine structure that mimic the action of the natural insect molting hormone 20-hydroxyecdysone.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.42%
- CAS 番号: 112226-61-6
- 分子式: C18H19ClN2O2
- 分子量:330.81
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
Halofenozide (RH-0345) reduces both growth and development of oocytes in vitro[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:Cultured ovaries were dissected from female adult beetles of mealworm, Tenebrio molitor (T. molitor)
-
Concentration:1 μM and 10 μM
-
Incubation Time:4 days
-
Result:Did not cause a significant effect on ecdysteroid amounts in the culture medium using ovaries from 0- and 2-day-old females at 10 μM.
Caused a small significant increase of the amounts of ovarian ecdysteroids in the culture medium at 1 μM in the culture medium and with 2-day-old ovaries.
Halofenozide at the two doses tested (5 and 10 μg) causes smaller eggs with a decrease in length, width and volume[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Newly emerged (0-day-old) adult females of T. molitor [1]
-
Dosage:5 and 10 μg
-
Administration:Topically applied
-
Result:Caused smaller eggs with a decrease in length, width and volume at the two doses tested (5 and 10 μg) .
化学情報
-
CAS 番号 112226-61-6
-
性状 Solid
-
分子量 330.81
-
分子式 C18H19ClN2O2
-
Color White to off-white
-
SMILES
O=C(NN(C(C1=CC=CC=C1)=O)C(C)(C)C)C2=CC=C(Cl)C=C2
-
別名
RH-0345
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 125 mg/mL (377.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (272 KB)
-
SDS (537 KB)
- English - EN (537 KB)
- Français - FR (537 KB)
- Deutsch - DE (537 KB)
- Norwegian - NO (537 KB)
- Español - ES (537 KB)
- Swedish - SV (537 KB)
- Italian - IT (537 KB)
- Portuguese - PT (537 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0229 mL | 15.1144 mL | 30.2288 mL | 75.5721 mL |
| 5 mM | 0.6046 mL | 3.0229 mL | 6.0458 mL | 15.1144 mL | |
| 10 mM | 0.3023 mL | 1.5114 mL | 3.0229 mL | 7.5572 mL | |
| 15 mM | 0.2015 mL | 1.0076 mL | 2.0153 mL | 5.0381 mL | |
| 20 mM | 0.1511 mL | 0.7557 mL | 1.5114 mL | 3.7786 mL | |
| 25 mM | 0.1209 mL | 0.6046 mL | 1.2092 mL | 3.0229 mL | |
| 30 mM | 0.1008 mL | 0.5038 mL | 1.0076 mL | 2.5191 mL | |
| 40 mM | 0.0756 mL | 0.3779 mL | 0.7557 mL | 1.8893 mL | |
| 50 mM | 0.0605 mL | 0.3023 mL | 0.6046 mL | 1.5114 mL | |
| 60 mM | 0.0504 mL | 0.2519 mL | 0.5038 mL | 1.2595 mL | |
| 80 mM | 0.0378 mL | 0.1889 mL | 0.3779 mL | 0.9447 mL | |
| 100 mM | 0.0302 mL | 0.1511 mL | 0.3023 mL | 0.7557 mL |