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製品番号: HY-137156

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NB-64

NB-64 is an orally active HIV-1 inhibitor. NB-64 is promising for research of HIV infections.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 53242-68-5
分子式: C₁₁H₈ClNO₂
分子量:221.64

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

NB-64 構造式

CAS 番号: 53242-68-5

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

NB-64 is an orally active HIV-1 inhibitor. NB-64 is promising for research of HIV infections^[1].

IC₅₀ & Target

HIV-1

HIV アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
MT2	CC₅₀	>4000 μM Compound: 15ii, NB-64	Toxicity against human MT2 cells Toxicity against human MT2 cells	[PMID: 26116177]
MT2	CC₅₀	335.7 μM Compound: 1, NB-64	Cytotoxicity against human MT2 cells after 4 days using XTT assay Cytotoxicity against human MT2 cells after 4 days using XTT assay	[PMID: 22014749]
MT2	CC₅₀	335.72 μM Compound: A1, NB-64	Cytotoxicity against human MT2 cells after 4 days by XTT assay Cytotoxicity against human MT2 cells after 4 days by XTT assay	[PMID: 19053778]
MT2	EC₅₀	2.39 μM Compound: A1, NB-64	Antiviral activity against HIV1 3B in human MT2 cells assessed as inhibition of p24 antigen level after 4 days by ELISA Antiviral activity against HIV1 3B in human MT2 cells assessed as inhibition of p24 antigen level after 4 days by ELISA	[PMID: 19053778]
MT2	EC₅₀	2.4 μM Compound: 1, NB-64	Antiviral activity against HIV1 3B infected in human MT2 cells assessed as inhibition of p24 production after 4 days by ELISA Antiviral activity against HIV1 3B infected in human MT2 cells assessed as inhibition of p24 production after 4 days by ELISA	[PMID: 22014749]
MT2	EC₅₀	29.92 μM Compound: 15ii, NB-64	Antiviral activity against HIV1 3B assessed as inhibition of virus mediated cell fusion between MT2 cells and H9/HIV1 3B cells Antiviral activity against HIV1 3B assessed as inhibition of virus mediated cell fusion between MT2 cells and H9/HIV1 3B cells	[PMID: 26116177]
U373-MAGI	CC₅₀	>4000 μM Compound: 15ii, NB-64	Toxicity against human U373-MAGI-CXCR4-CEM cells Toxicity against human U373-MAGI-CXCR4-CEM cells	[PMID: 26116177]
U-87MG ATCC	CC₅₀	>4000 μM Compound: 15ii, NB-64	Toxicity against human U87-T4-CXCR4 cells Toxicity against human U87-T4-CXCR4 cells	[PMID: 26116177]

化学情報

CAS 番号 53242-68-5
分子量 221.64
分子式 C₁₁H₈ClNO₂
SMILES

O=C(C1=CC(N2C=CC=C2)=CC=C1Cl)O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (267 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Jiang S, et al. N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion. Antimicrob Agents Chemother. 2004 Nov;48(11):4349-59. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

生物活性
- 製品説明
- IC₅₀ & Target
化学情報
純度とドキュメンテーション
参考文献

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NB-64

HIV アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

NB-64 関連分類

HY-137156 関連分類