OXi8007
Based on 1 Customer Validation
OXi8007 is a water-soluble phosphate proagent of OXi8006, a tubulin-binding compound.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.48%
- CAS 番号: 288847-41-6
- 分子式: C26H24NNa2O10P
- 分子量:587.42
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| DU-145 | GI50 |
0.0297 μM
Compound: 33, OXi8007
|
Cytotoxicity against human DU145 cells by SRB assay
Cytotoxicity against human DU145 cells by SRB assay
|
[PMID: 24016002] |
| NCI-H460 | GI50 |
0.0311 μM
Compound: 33, OXi8007
|
Cytotoxicity against human NCI-H460 cells by SRB assay
Cytotoxicity against human NCI-H460 cells by SRB assay
|
[PMID: 24016002] |
| SK-OV-3 | GI50 |
0.0223 μM
Compound: 33, OXi8007
|
Cytotoxicity against human SKOV3 cells by SRB assay
Cytotoxicity against human SKOV3 cells by SRB assay
|
[PMID: 24016002] |
化学情報
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CAS 番号 288847-41-6
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性状 Solid
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分子量 587.42
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分子式 C26H24NNa2O10P
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Color Off-white to light yellow
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SMILES
O=P(OC1=CC(C(NC2=C3C=CC(OC)=C2)=C3C(C4=CC(OC)=C(C(OC)=C4)OC)=O)=CC=C1OC)(O[Na])O[Na]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
体外:
H2O : ≥ 100 mg/mL (170.24 mM)
DMSO : 90 mg/mL (153.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 1.7024 mL | 8.5118 mL | 17.0236 mL | 42.5590 mL |
| 5 mM | 0.3405 mL | 1.7024 mL | 3.4047 mL | 8.5118 mL | |
| 10 mM | 0.1702 mL | 0.8512 mL | 1.7024 mL | 4.2559 mL | |
| 15 mM | 0.1135 mL | 0.5675 mL | 1.1349 mL | 2.8373 mL | |
| 20 mM | 0.0851 mL | 0.4256 mL | 0.8512 mL | 2.1279 mL | |
| 25 mM | 0.0681 mL | 0.3405 mL | 0.6809 mL | 1.7024 mL | |
| 30 mM | 0.0567 mL | 0.2837 mL | 0.5675 mL | 1.4186 mL | |
| 40 mM | 0.0426 mL | 0.2128 mL | 0.4256 mL | 1.0640 mL | |
| 50 mM | 0.0340 mL | 0.1702 mL | 0.3405 mL | 0.8512 mL | |
| 60 mM | 0.0284 mL | 0.1419 mL | 0.2837 mL | 0.7093 mL | |
| 80 mM | 0.0213 mL | 0.1064 mL | 0.2128 mL | 0.5320 mL | |
| 100 mM | 0.0170 mL | 0.0851 mL | 0.1702 mL | 0.4256 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.