PB038
Based on 1 Customer Validation
PB038 is a Drug-liker containing a PEG unit and a cleavable linker attached to Exatecan.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.99%
- CAS 番号: 2851058-71-2
- 分子式: C98H149FN12O36
- 分子量:2090.29
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Drug-Linker Conjugates for ADC アイソフォーム固有の製品をすべて表示
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生物活性
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2851058-71-2
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性状 Solid
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分子量 2090.29
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分子式 C98H149FN12O36
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Color Off-white to yellow
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SMILES
O=C(N1CCCCCC(N[C@H](C(N[C@H](C(N[C@H](C(NC2=CC=C(COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@]7(CC)O)=C(C6=O)COC7=O)=NC8=CC(F)=C(C(CC3)=C84)C)=O)C=C2)=O)CCCNC(N)=O)=O)C(C)C)=O)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN(C[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)C[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O)=O)=O)C=CC1=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (47.84 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (281 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.4784 mL | 2.3920 mL | 4.7840 mL | 11.9601 mL |
| 5 mM | 0.0957 mL | 0.4784 mL | 0.9568 mL | 2.3920 mL | |
| 10 mM | 0.0478 mL | 0.2392 mL | 0.4784 mL | 1.1960 mL | |
| 15 mM | 0.0319 mL | 0.1595 mL | 0.3189 mL | 0.7973 mL | |
| 20 mM | 0.0239 mL | 0.1196 mL | 0.2392 mL | 0.5980 mL | |
| 25 mM | 0.0191 mL | 0.0957 mL | 0.1914 mL | 0.4784 mL | |
| 30 mM | 0.0159 mL | 0.0797 mL | 0.1595 mL | 0.3987 mL | |
| 40 mM | 0.0120 mL | 0.0598 mL | 0.1196 mL | 0.2990 mL |