CPA4
null CPA4, or membrane-bound carboxypeptidase, distinguishes itself within the carboxypeptidase A subfamily by its tight association with the cell surface rather than secretion into digestive juice. It is a zinc metalloenzyme with metallocarboxypeptidase activity toward C-terminal aliphatic and aromatic residues of small peptide substrates. CPA4 is highly expressed in prostate and is markedly upregulated in hormone-refractory prostate cancer, where it has been proposed to support androgen-independent growth and has attracted interest as a biomarker and therapeutic target. Expression is also observed in other tissues and tumor types, and recombinant CPA4 supports studies of extracellular peptide processing in cancer biology.
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CPA4 組換えタンパク質 (1)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- 分子式: Human
- 分子量: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
