q-FTAA
Based on 1 Customer Validation
q-FTAA is an oligothiophene. q-FTAA competes for binding to the X-34 binding site on Aβ fibrils. q-FTAA is applicable to research related to Alzheimer's disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 97.06%
- CAS 番号: 1352477-22-5
- 分子式: C21H14O6S4
- 分子量:490.59
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
q-FTAA (1 μM) competes with 3H-X-34 for binding to recombinant Aβ1-42 fibrils, with an EC50 of 330-630 nM[1].
q-FTAA competes with 3H-X-34 for binding to Aβ deposits (ADPBC) purified from human AD brains, with an EC50 of 300-500 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
化学情報
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CAS 番号 1352477-22-5
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性状 Solid
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分子量 490.59
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分子式 C21H14O6S4
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Color Yellow to orange
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SMILES
O=C(C1=CC=C(C2=CC(CC(O)=O)=C(C3=CC=C(C4=C(CC(O)=O)C=CS4)S3)S2)S1)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 31.25 mg/mL (63.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
純度とドキュメンテーション
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データシート (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0384 mL | 10.1918 mL | 20.3836 mL | 50.9590 mL |
| 5 mM | 0.4077 mL | 2.0384 mL | 4.0767 mL | 10.1918 mL | |
| 10 mM | 0.2038 mL | 1.0192 mL | 2.0384 mL | 5.0959 mL | |
| 15 mM | 0.1359 mL | 0.6795 mL | 1.3589 mL | 3.3973 mL | |
| 20 mM | 0.1019 mL | 0.5096 mL | 1.0192 mL | 2.5480 mL | |
| 25 mM | 0.0815 mL | 0.4077 mL | 0.8153 mL | 2.0384 mL | |
| 30 mM | 0.0679 mL | 0.3397 mL | 0.6795 mL | 1.6986 mL | |
| 40 mM | 0.0510 mL | 0.2548 mL | 0.5096 mL | 1.2740 mL | |
| 50 mM | 0.0408 mL | 0.2038 mL | 0.4077 mL | 1.0192 mL | |
| 60 mM | 0.0340 mL | 0.1699 mL | 0.3397 mL | 0.8493 mL |
q-FTAA 関連分類
HY-148547 関連分類
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